Flexeril has potential interaction with inebriant , some other drugs , and sure supplements . Examples include opioids and sure antidepressants . spill with your doctor to avoid potentially harmful effects from cyclobenzaprine fundamental interaction .

Cyclobenzaprine unwritten tablet is agenericdrug order for muscle spasms due to painfulmusculoskeletalconditions , such asmuscle strainsor injuries . It ’s prescribed for this utilisation in adults and baby ages 15 years and older . It ’s prescribed for little - terminal figure use ( up to 3 weeks ) , along with rest and strong-arm therapy .

Cyclobenzaprine is available as the brand - name drug Amrix .

Aninteractionoccurs when one substance cause another message to have a different effect than await . By find out about possible cyclobenzaprine fundamental interaction , you could function with your Doctor of the Church to ensure cyclobenzaprine will be dependable and effective for you to take .

For additional data about cyclobenzaprine , including item about its habit , see thiscyclobenzaprineoverview article .

Cyclobenzaprine interactions with other drugs

Before you start treatment with cyclobenzaprine oral tablet , evidence your doctor and apothecary about any prescription , over - the - replication , and other medication you take . By share this information with them , you may help prevent possible fundamental interaction .

To learn whether Flexeril interact with supplement , herbs , or vitamin , see the “ Cyclobenzaprine and other interaction ” subdivision .

If you have doubtfulness about drug interactions that may affect you , ask your doctor or pharmacist .

Here ’s a table of drug that can interact with Flexeril . Keep in mind this table does n’t include all drugs that may interact with Flexeril . Some of these interactions are described in detail in “ Drug interactions in depth . ”

Optum Perks is possess by RVO Health . By press this link , we may receive a commission . study more .

When to avoid cyclobenzaprine

In some case , certain factors or conditions could prevent your medico from prescribing cyclobenzaprine due to the risk of impairment . These are known as contraindications . Below are the contraindications of cyclobenzaprine .

Note : Before you bulge treatment with Flexeril , it ’s important to order your doctor if these contraindication practice to you . They can square up whether to prescribe Flexeril .

Having certain heart conditions

Doctors typically will not prescribe Flexeril for people with the watch heart conditions :

Flexeril can cause a firm or atypical heartbeat , which can be dangerous for people with these heart conditions .

If you have one of these affectionateness conditions , utter with your doctor before taking Flexeril . They ’ll in all probability prescribe a treatment other than cyclobenzaprine for your condition .

Having hyperthyroidism

Doctors typically will not prescribe cyclobenzaprine for people withhyperthyroidism . This is because hyperthyroidism can make a fast or unpredictable split second , and cyclobenzaprine can make this speculative .

If you have hyperthyroidism , mouth with your doctor before taking Flexeril . They ’ll in all likelihood prescribe a treatment other than Flexeril for your precondition .

Taking a monoamine oxidase inhibitor

Doctors typically will not prescribe cyclobenzaprine in combination with a type of drug called amonoamine oxidase inhibitor ( MAOI)or drug that have a alike chemical mechanism of legal action to MAOIs .

Taking cyclobenzaprine with an MAOI can increase your risk of exposure of serious side effect , includingseizuresandserotonin syndrome . With this syndrome , your body has a high stage of a brain chemical substance calledserotonin . This can cause symptom such as blood pressure changes , excessive sweating , and chuck . 5-hydroxytryptamine syndrome can be aliveness imperil for some people .

MAOIs that can interact with cyclobenzaprine include :

Before you start handling with cyclobenzaprine , it ’s important to enjoin your medico if you take an MAOI . They ’ll probably not prescribe cyclobenzaprine . you may talk with them about other intervention options for your consideration . Likewise , after you stop taking Flexeril , your doctor will typically have you await at least 2 week before bulge out treatment with an MAOI .

Having had an allergic reaction to cyclobenzaprine or any of its ingredients

If you have had anallergic reactionto Flexeril or any of its ingredients , your Dr. will likely not prescribe Flexeril . Taking the drug could cause another supersensitized chemical reaction . you could take them about other treatment that may be better choices for you .

For warnings about other health factors that may interact with cyclobenzaprine , see “ Flexeril and wellness - related interactions . ” If you have questions about what to avoid when takingmuscle relaxerssuch as Flexeril , verbalise with your doctor or druggist .

Cyclobenzaprine interaction with alcohol

If you drinkalcohol , your doctor will in all probability commend that you do not pledge it while taking cyclobenzaprine .

Consuming alcohol and taking Flexeril may have serious side effects , let in :

The compounding of alcohol and Flexeril may also , in some caseful , lead to death . If you drink alcoholic drink and have fear about avoiding it while you ’re pick out cyclobenzaprine , sing with your doc before starting treatment .

Drug interactions in depth

Here ’s a unaired look at sure drug interactions of cyclobenzaprine .

Opioids

Opioidsare strong pain - allay medications . Taking cyclobenzaprine with opioids can cause serious side effects .

Flexeril and opioids are bothCNSdepressants . This mean they slow activity in your encephalon and spinal corduroy . Taking cyclobenzaprine with opioids can raise your risk ofCNS low . CNS depression can cause symptom such as :

In knockout cases , CNS depression may direct to tiresome , decrepit breathing , loss of cognizance , coma , or expiry .

Cyclobenzaprine and certain opioids can both have a serious side essence calledserotonin syndrome . With this syndrome , your consistence has a high-pitched spirit level of a encephalon chemical substance called serotonin . Taking Flexeril with certain opioids can raise your risk of serotonin syndrome . Serotonin syndrome can cause symptom such as blood pressure change , extravagant sweating , andnausea and vomiting . This syndrome can be life endanger for some the great unwashed .

Taking Flexeril with opioids can also upraise your risk ofsevere constipation . stultification is a side effect of both drugs .

Here are some opioids that may interact with Flexeril :

Your doctor will ordinarily avoid prescribing cyclobenzaprine with opioids . If they do dictate these medication together , they may prescribe a lower than common dose of one or both medications .

If you take cyclobenzaprine with an opioid , tell apart your doctor right forth if you have symptoms of CNS depression or serotonin syndrome .

If you have questions about take cyclobenzaprine with opioids , blab out with your doctor or pharmacist .

Antidepressants

occupy cyclobenzaprine withantidepressantscan call down your risk of serious side effects .

Flexeril and antidepressants can both cause serotonin syndrome as a side effect . Taking Flexeril with antidepressant drug can raise your risk of infection of this potentially life threatening side burden .

Some antidepressant , such astricyclics , are CNS depressants . take Flexeril ( a CNS depressant ) with these antidepressant can grow your risk of CNS depression .

you may find details about serotonin syndrome and CNS depression in the “ Opioids ” section .

Taking cyclobenzaprine with tricyclic antidepressants can also lift your risk ofurination problemsand austere stultification . These are potential side effect of both drugs .

Here are some antidepressants that may interact with cyclobenzaprine :

  • Your doctor likely will not order cyclobenzaprine with MAOIs . For more information , see “ When to deflect Flexeril . ”

If you take an antidepressant , tattle with your doctor before exact cyclobenzaprine . In some cases , your Doctor of the Church may avoid prescribing Flexeril . you may talk with them about alternatives that may be safer for you .

If your doctor prescribe cyclobenzaprine with your antidepressant , they may order a dosage of either medicament that ’s modest than common . Talk with your physician about what side effect to look out for and what to do if you get them . If you have symptoms of serotonin syndrome , you should babble out with your MD right aside .

If you have questions about taking cyclobenzaprine with antidepressants , talk with your doctor or pharmacist .

Certain blood pressure medications

Cyclobenzaprine has interaction with certain blood insistency medications .

Here are some blood pressure medication that may interact with Flexeril :

Taking Flexeril with clonidine can make clonidine less efficient at lower your blood pressure . It can also raise your risk of drowsiness , as both medications can cause drowsiness .

guide cyclobenzaprine with Isoptin can raise your risk of serotonin syndrome . This is a serious side effect that can be lifetime threaten for some mass . you may find details about serotonin syndrome in the “ Opioids ” section .

lead cyclobenzaprine with other blood pressure medicinal drug does n’t usually cause an fundamental interaction . However , cyclobenzaprine and blood pressure medications can both make dizziness . So you may have a high-pitched risk of this side effect if you take these medications together .

If you take blood pressure medicinal drug , talk with your medico before taking cyclobenzaprine . In some casing , your MD may avoid prescribing cyclobenzaprine . you could verbalise with them about alternatives that may be safe for you .

If your doctor prescribes Flexeril with your line pressure medication , they may prescribe adosage of cyclobenzaprinethat ’s scummy than common . severalise your Dr. if you have raw or increased vertigo or drowsiness .

If you take cyclobenzaprine with Catapres , your doctor maymonitoryour blood pressure more closely . If you take cyclobenzaprine with verapamil , tattle with your MD right forth if you have symptoms of serotonin syndrome .

If you have doubtfulness about take Flexeril with blood imperativeness medications , talk with your physician or apothecary .

Cyclobenzaprine and other interactions

Cyclobenzaprine may have other interactions , such as with supplements , foods , vaccinum , or lab test .

Here are some potential interactions with cyclobenzaprine . Keep in mind that the come after information does not include all other possible Flexeril interactions .

Cyclobenzaprine interactions with supplements

Before you start treatment with Flexeril , tell your doctor and apothecary about anysupplements , herb , andvitaminsyou take . By sharing this information with them , you may help prevent potential interaction .

Cyclobenzaprine can interact with certain herbs .

Valerian : It ’s possible for Flexeril to interact with herb that can stimulate somnolence , such asvalerian . Some citizenry employ this herb to aid sopor . If you take valerian during Flexeril treatment , it may increase sleepiness .

If you take any valerian supplements , talk with your doctor before starting Flexeril discourse . They may give notice you to stop taking the postscript while you ’re have Flexeril . Or they may recommend take a lower dosage of valerian or Flexeril .

St. John ’s wort : Doctors will typically recommend you deflect takingSt . John ’s wortwith Flexeril . St. John ’s wort is an herbal supplement that may be used to treatdepressionand other conditions .

learn St. John ’s wort with cyclobenzaprine may raise your hazard of a serious side effect calledserotonin syndrome . With this syndrome , your body has a high stage of a brain chemical called serotonin . This can cause symptoms such as descent pressure changes , excessive sweating , diarrhea , nausea , and vomiting . 5-hydroxytryptamine syndrome can be life jeopardise for some people .

Your Dr. may be able to suggest a treatment option other than St. John ’s wort .

There are no specificreportsof vitamin interacting with cyclobenzaprine . However , that does n’t have in mind vitamin interaction wo n’t occur or be acknowledge in the future . Because of this , you should speak with your doctor or pill roller before taking any vitamin product with Flexeril .

Cyclobenzaprine interactions with food

There were noreportsof food interaction with Flexeril . If you ’d like to learn more about eating sure foods during treatment with cyclobenzaprine , talk with your medico .

Cyclobenzaprine interactions with vaccines

There are n’t any known interaction between cyclobenzaprine andvaccines . Talk with your doctor or pharmacist to check whether you ’re due for any vaccines .

Cyclobenzaprine interactions with lab tests

Cyclobenzaprine is n’t know to interact with research lab tests . If you have concerns about this medicine interacting with lab tests , babble out with your doctor .

Cannabis(often telephone marijuana ) and cannabis product , such as cannabidiol ( CBD ) , have been specificallyreportedto interact withAmrix(a brand name - name translation of Flexeril ) .

Flexeril and marijuana are bothCNSdepressants . This mean that they slow activeness in your encephalon and spinal corduroy . Taking Flexeril with cannabis or cannabis product can raise your risk ofCNS slump . CNS natural depression can cause symptom such as somnolence , dizziness , and disarray .

Taking cyclobenzaprine with marihuana or cannabis products can make cyclobenzaprine make up in your consistency . This can recruit your jeopardy of side effect from cyclobenzaprine .

Before you begin treatment with cyclobenzaprine , tell your doctor and pharmacist if you use cannabis . By sharing this information with them , you may help prevent possible interactions .

Note : Cannabis is illegal at a Union stage but is legal in many U.S. states to vary degrees .

sure medical conditions and other factors may increase the risk of interactions with cyclobenzaprine . Before you take this drug , be certain to talk with your doctor about your wellness chronicle . Cyclobenzaprine may not be the ripe treatment option if you have sure medical circumstance or other factors affecting your health .

Health status or factors that might interact with cyclobenzaprine include :

FAQ about cyclobenzaprine and interactions

Here are some oftentimes need questions about cyclobenzaprine and possible interactions .

Does cyclobenzaprine have interactions with ibuprofen?

No , cyclobenzaprine is not know to interact withibuprofen(Advil , Motrin ) . It ’s in general considered safe to take these medications together .

Your doctor may recommend taking Flexeril with Advil if you have a painful muscle melodic line or trauma . Flexeril helps relax the injured musculus and exempt the pain , while ibuprofen reduces redness ( swelling ) link up to the injury . This can also serve relieve the pain .

If you have questions about taking cyclobenzaprine with Nuprin , talk with your doctor .

Can you drink coffee while taking cyclobenzaprine?

Yes , it ’s usually secure to drinkcoffeewhile you ’re taking Flexeril . Coffee containscaffeine , which is aCNS stimulantthat can help counteract sleepiness that you may have with Flexeril .

mark that on rare occasions , cyclobenzaprine may cause increasedheart rate , center vibration , agitation , oranxiety . If you have these side effects , drinking coffee could make them bad , as caffeinated deep brown can also do these side upshot .

If you have dubiousness about drink coffee with Flexeril , talk with your doctor or pharmacist .

Preventing interactions

you may take sure step to help prevent fundamental interaction with cyclobenzaprine . Your medico and chemist are key resources , so strive out to them before set about treatment . For model , you should plan to do the followers :

It ’s also important to record the cyclobenzaprine label and otherpaperworkthat may come with the drug . The recording label may have colored paster that mention an interaction . The paperwork , sometimes called the medicament templet or patient bundle insert , may comprise detail about interactions .

If Flexeril does n’t come with paperwork , you may involve your druggist to print a written matter . If you call for help reading or understanding this information , ask your doctor or pharmacist .

you’re able to also help prevent interaction with Flexeril by taking it precisely as your physician prescribes .

Disclaimer : Medical News Today has made every effort to ensure that all information is factually correct , comprehensive , and up to date . However , this article should not be used as a substitute for the cognition and expertise of a commissioned healthcare professional . You should always confer your doctor or another health care professional before taking any medicament . The drug information contained herein is capable to alteration and is not mean to cover all possible uses , directions , precautions , warnings , drug interactions , sensitised reactions , or adverse core . The absence of warning or other entropy for a given drug does not indicate that the drug or drug combination is safe , effective , or appropriate for all patients or all specific use .