Fabrazyme ( agalsidase genus Beta ) is a brand - name endovenous ( IV ) extract that ’s order for Fabry disease in adults and certain children . As with other drug , Fabrazyme can cause side effects , such as infusion reactions and respiratory infections .
More common side effects of Fabrazyme
Fabrazyme can have certain side essence , some of which are more coarse than others . These side outcome may be temporary , lasting a few days to weeks . However , if the side effects last longer than that , get to you , or become severe , be sure to talk with your Doctor of the Church or pharmacist .
These are just a few of the more common side force reported by people who took Fabrazyme inclinical trials :
For more info about some of these side effects , see the “ Side force specifics ” segment .
Mild side effects of Fabrazyme
meek side effects can occur with Fabrazyme function . This list does n’t let in all potential soft side effects of the drug . For more information , you may have-to doe with to Fabrazyme’sprescribing information .
meek side consequence that have been reported with Fabrazyme include :
These side burden may be temporary , lasting a few days to weeks . However , if the side effects continue , worsen , or become too difficult to stand , be sure to talk with your medico or pharmacist .
Serious side effects of Fabrazyme
Fabrazyme may cause serious side effect . The list below may not let in all possible serious side effect of the drug . For more information , you’re able to refer to Fabrazyme’sprescribing selective information .
If you develop serious side effects while taking Fabrazyme , call your doctor the right way off . If the side effects seem life threatening or you consider you ’re bear a medical emergency , immediately call 911 or your local emergency number .
Serious side effects that have been reported and their symptoms include :
For some people , Fabrazyme can cause anallergic reaction .
In universal , symptoms of hypersensitive reaction can be mild or serious . Mild symptom can admit a mild rash , itching , and flushing ( redness or deepening of tegument color and feeling red-hot ) . Serious symptom can admit dizziness , trouble breathing , and intumesce , typically in your face , lips , tongue , throat , script , or feet .
slipway to deal
If you have any symptoms of an hypersensitised reaction during your infusion , tell the health care professional administering your infusion decently away . They may give you medications or other treatments to reduce your symptom . They may also slow up , break , or lay off your infusion .
If you have mild supersensitive reaction symptoms after receiving an infusion , call your doctor right off . They may recommend treatments to aid manage your symptom . They ’ll also let you have it away whether you should get further medical care and whether you should keep receive the medicinal drug in future .
If you have wicked allergic reaction symptom after find an extract , call 911 or your local emergency number right on aside . These symptoms require immediate medical care because they can become lifespan threatening . If you ’ve had a serious supersensitive reaction to Fabrazyme , your doctor may recommend taking a different medicament alternatively .
Side effect specifics
Learn more about some of the side effects that Fabrazyme may induce . To find out how often side effects happen in clinical trial , see theprescribing informationfor Fabrazyme .
Infusion reactions
Fabrazyme is administered by IV extract , which is an injection into a vein that ’s given over a flow of time . Fabrazyme infusions are unremarkably fall in over a few hours .
extract reactionsare irregular symptoms that you may have during a Fabrazyme extract or later that Clarence Shepard Day Jr. . Inclinical trials , extract reaction were very unremarkably reported with Fabrazyme .
Symptoms of infusion reactions can be mild or severe . They can admit :
If you have infusion reactions , these run to become milder and less frequent with continued Fabrazyme treatment . But you may still have reaction even when you ’ve been receiving the treatment for a long time .
If your physical structure make antibodies to Fabrazyme , you may be more likely to have infusion reactions . ( antibody are protein that yourimmune systemmakes to help protect you from strange substances . Your doc may order tests to confirm whether your soundbox makes antibodies to Fabrazyme . ) And if you have heart problems , you may have a eminent jeopardy of severe ramification from infusion reactions .
To help preclude or reduce infusion chemical reaction , your doctor will likely prescribe sure medications before each infusion of Fabrazyme . These are call premedications or pre - meds .
For example , your doctor may dictate :
If you have symptom of an extract reaction while receiving Fabrazyme , tell the healthcare master administer your infusion right away . They may give you more doses of your premedication to treat your symptom . They may also slow down or pause your infusion .
If you have wicked symptoms , your healthcare professional may stop your infusion . And they may give you other treatment , such asoxygen , bronchodilators , orepinephrine .
If you have an infusion reaction , your doctor may take down yourFabrazyme dosagefor your next infusion . They may also give your next infusion over a retentive menses of time .
If you have questions about the risk of extract reaction with Fabrazyme , sing with your doctor .
Upper respiratory infections
You may have a elevate risk of gettingupper respiratory infectionssuch as coughs , coldness , and sinusitis while receiving Fabrazyme .
Inclinical trials , upper respiratory infections and their symptoms were commonly reported in masses receiving Fabrazyme .
Symptoms of upper respiratory infection can include :
Note that some of these symptom can also be symptoms of infusion reaction ( see just above ) .
If you have symptom of an upper respiratory infection , you’re able to require your Doctor of the Church or pill roller to commend an over - the - parry medicinal drug to free your symptoms .
For example , they may recommend :
lecture with your doctor or druggist about what medicinal drug may be right for you .
If you have severe symptoms or symptoms that do n’t go aside , talk with your MD . They can avail determine the cause of your symptom and whether you need another treatment . For example , if you have bacterial sinusitis , your doctor may prescribe anantibioticto treat the transmission .
If you have questions about the risk of respiratory infections with Fabrazyme , talk with your doctor or apothecary .
Precautions for Fabrazyme
Before taking Fabrazyme , hash out your health history with your doctor . Fabrazyme may not be right for you if you have sure aesculapian conditions or other ingredient move your health . Be certain to sing with your doctor if any of the following use to you :
- Antibodies are proteins that your resistant organisation makes to aid protect you from strange substances . Your doctor may put tests to correspond if your trunk induce antibodies to Fabrazyme .
Disclaimer : Medical News Today has made every effort to verify that all information is factually correct , comprehensive , and up to date . However , this article should not be used as a substitute for the cognition and expertise of a licensed health care professional . You should always consult your Dr. or another healthcare professional before taking any medication . The drug info contained herein is subject to alteration and is not intended to cover up all possible economic consumption , directions , caution , warnings , drug interactions , allergic reactions , or contrary effect . The absence of warning or other information for a give drug does not point that the drug or drug combination is safe , effective , or appropriate for all patient or all specific uses .