Gomekli is a brand - name drug prescribed for sure noncancerous tumors . The medication is available as an oral capsule and oral lozenge .
Specifically , the Food and Drug Administration ( FDA ) has okay Gomekli to treatneurofibromatosis type 1 - associated plexiform neurofibromas ( NF1 - PN ) . With this condition , noncancerous tumors grow on nerves outside the brain and spinal corduroy . Gomekli is used to treat NF1 - PN in certain adult and fry ages 2 years and sr. .
Drug details
You ’ll find key info about Gomekli here :
Gomekli generic
Gomekli is useable only as a brand - name medication . It ’s not currently uncommitted ingeneric form .
A generic drug is an exact copy of the fighting ingredient in a brand - name medicament . Generics normally be less than trade name - name drugs .
Gomekli dosage
The Gomekli dosage your doc prescribes will depend on certain factors , including :
Your MD will shape your BSA using your meridian and free weight . BSA is measured in meters square ( m2 ) .
The following information describes dosage that are usually used or recommend . However , be sure to take the dose your MD prescribes for you . Your Dr. will decide the good dosage to conform to your needs .
Drug forms and strengths
Gomekli fall in the follow form and strengths :
To learn more about necessitate each form of Gomekli , see the “ How to take ” section .
Dosage for NF1-PN
Gomekli is prescribed to treatneurofibromatosis eccentric 1 - link plexiform neurofibromas ( NF1 - PN)in certain situations . To acquire more , see the “ Gomekli uses ” section .
The typical dosage of Gomekli for NF1 - PN is 2 mg / m² taken doubly a day for 3 calendar week , come by a 1 - week break .
For illustration , if your medico determines your BSA is 1.5 m2 , your dosage would be 4 mg twice a day for 3 hebdomad . This would be come after by 1 week without the drug before restarting it the next week .
Your Doctor of the Church will apprize you on how long you ’ll take Gomekli .
Children’s dosage
Gomekli is prescribed to do by NF1 - PN in sure children ages 2 old age and sr. .
The dosage of Gomekli for children is the same as for grownup . For details , see “ Dosage for NF1 - PN . ”
How to take
You ’ll bury Gomekli capsules whole . you could also get down Gomekli tablet whole or unthaw them in water to form a suspension that you booze .
About taking Gomekli
You ’ll find information about key dosage issues here :
Overdose
Do not take more Gomekli than your MD recommend . For some drugs , doing so may lead to undesirable side effects or overdose .
If you mean you ’ve take too much of this drug , call your doctor . you’re able to also call America ’s Poison Centers at 800 - 222 - 1222 or expend itsonline tool . However , if your symptoms are grievous , call 911 or your local pinch act or go to the nearest emergency room aright away .
Gomekli side effects
Gomekli can cause mild or serious side effects . The keep an eye on inclination contain some of the key side effects that may come about while have Gomekli . These lists do not include all possible side effect .
For more information about the potential side effects of Gomekli , talk with your doctor or pharmacist . They can give you steer on how to manage any side personal effects that may headache or inconvenience you .
observe : After the Food and Drug Administration ( FDA ) okay a drug , it tracks and brush up side effects of the medication . Sharing your experience helps make medications dependable for everyone by give doctors and researchers more information about how the drug works in veridical life . If you develop a side issue while take Gomekli and require to tell the FDA about it , visitMedWatchor call 800 - FDA-1088 .
Mild side effects
Here is a partial list of mild side effect of Gomekli . To check about other mild side effects , lecture with your medico or pharmacist , or view Gomekli’sprescribing entropy .
Mild side effect of Gomekli can admit :
Most of these side effect may go aside within a few days to a span of week . However , if they become more grievous or do n’t go away , talk with your MD or pharmacist .
Serious side effects
Serious side effects from Gomekli are n’t vulgar , but they can occur . Call your physician right on away if you have serious side effects . Call 911 or your local emergency phone identification number if your symptom feel life threatening or you mean you ’re having a aesculapian emergency .
Serious side effects and their symptoms can include :
Side effects in children
Gomekli is approved to treatneurofibromatosis type 1 - colligate plexiform neurofibromas ( NF1 - PN)in children ages 2 years and older .
Most side effects of Gomekli are similar in kid and adults . However , certain side effects may be more common in child . Examples include :
If you ’re concerned about the side effects of Gomekli in small fry , talk with your child ’s doctor or pharmacist .
For some people , Gomekli can cause anallergic reaction . But this side burden was n’t reported in the drug’sclinical trials .
In ecumenical , symptoms of an allergic response can be modest or serious .
Ways to manage
For balmy allergic reaction symptom , such as a meek blizzard , call your doctor right away . They may recommend discussion to help manage your symptoms . They ’ll also let you know whether you should keep taking the medicine .
For severe allergic reaction symptoms , such as swelling or trouble breathing , call 911 or your local hand brake act right off . These symptoms require immediate medical care because they can become life threaten . If you ’ve had a serious allergic reaction to Gomekli , your physician may recommend a unlike medication instead .
Gomekli uses
The Food and Drug Administration ( FDA ) approves prescription drug such as Gomekli to treat sure conditions .
Gomekli for NF1-PN
Gomekli is O.K. to treatneurofibromatosis case 1 - link plexiform neurofibromas ( NF1 - PN)in certain grownup .
Neurofibromatosis is a rarefied genic ( inherit ) term that increases the risk of exposure of tumor outgrowth . With NF1 - PN , tumors develop on nerves outside the brain and spinal cord . Symptoms may admit infliction , difficulty go , hearing , or breathing .
Gomekli is prescribed when the tumor are causing symptom but can not be remove with surgery .
To read more about Gomekli for NF1 - PN , babble with your doctor .
Gomekli and children
Gomekli is approved to care for NF1 - PN in children age 2 year and old . It ’s prescribed when tumors concern to NF1 - PN are causing symptoms but can not be polish off with operation .
To ascertain more about this use of goods and services , you’re able to also talk with your baby ’s doctor .
Gomekli interactions
Gomekli is not known tointeractwith other medicine , herbs , supplement , foods , or inebriant . The manufacturer of Gomekli did n’t look at interaction inclinical trialsof the drug .
However , this does n’t mean that interactions wo n’t be recognized in the future . For example , new drugs could be sanction that interact with Gomekli .
Before commence Gomekli discourse , talk with your MD and pharmacist . recite them about all prescription , over - the - return , and other drugs you take . Also say them about anyvitamins , herbs , and supplementsyou take . Sharing this information can assist you head off potential interaction .
If you have questions about drug interactions that may affect you , blab with your doctor or pharmacist .
Gomekli cost and coupons
As with all medicament , the monetary value of Gomekli can motley . The genuine cost you ’ll pay depends on yourinsuranceplan , your locating , and the pharmacy you expend .
fiscal and insurance help : If you demand financial support to pay for Gomekli or aid understanding your indemnity coverage , aid is available .
A course of study called SpringWorks CareConnections is uncommitted for Gomekli . For more information and to find out if you ’re eligible for living , call 844 - 227 - 3755 or visit theprogram site .
Generic version : Gomekli is not usable in agenericform . A generic drug is an exact copy of the active fixings in a brand - name medication . Generics run to cost less than brand - name drugs .
Similar drugs
Other drug are available that can treatneurofibromatosis eccentric 1 - affiliate plexiform neurofibromas ( NF1 - PN ) . For model , Koselugo ( selumetinib ) is also O.K. for this economic consumption .
Some drugs may be a better fit for you than others . If you ’re interested in determine an alternative to Gomekli , talk with your doctor . They can tell you about other medications that may work well for you .
Things to consider when taking Gomekli
If you’re able to become pregnant , consider the following information about pregnancy , fertility , birth control , and suckle .
Note : Sex and genderexist on spectrum . Use of the term “ distaff ” and “ male ” in this article refers to sexual urge assigned at birth .
Gomekli and pregnancy
Gomekli should not be taken during gestation .
If you ’re project a pregnancy or can become pregnant , talk with your doctor before shoot this medicinal drug . They ’ll in all probability give you apregnancy testbefore you start Gomekli treatment .
Gomekli and fertility
Inanimal written report , Gomekli decreased distaff fertility ( the power to conceive ) . However , fauna discipline do n’t always predict what will pass in humans .
Before begin Gomekli intervention , talk with your doctor about the drug ’s potential effects on fertility . They can commend whether Gomekli is the right treatment option .
Gomekli and birth control
Gomekli is not safe to take during gestation . If you ’re sexually combat-ready and you or your cooperator can become pregnant , spill the beans with your Dr. about yourbirth controloptions while you ’re taking Gomekli .
MD may advise female person who can become pregnant to practice parturition mastery during Gomekli treatment and for at least 6 week after the last VD . If you ’re a female pickings Gomekli , talk with your doctor about your birth control needs .
MD may advise males with a sexual partner who can become significant to use parturition control during Gomekli intervention and for at least 3 month after the final dose . If you ’re a male taking Gomekli , talk with your medico about your birth dominance needs .
Gomekli and breastfeeding
It is obscure whether Gomekli is safe to take while lactate . To be safe , it ’s recommend that you avoid wet-nurse during Gomekli discussion and for at least 1 week after your terminal dose .
If you ’re breastfeeding or planning to do so , talk with your doctor before starting Gomekli intervention .
Gomekli precautions
Before acquire Gomekli , discuss your health account with your medico . Gomekli may not be correct for you if you have certain medical conditions or other factors sham your health . Be sure to talk with your doctor if any of the surveil apply to you :
Note : For more selective information about the potential negative effect of Gomekli , see the “ Gomekli side effects ” department .
Disclaimer : Medical News Today has made every effort to make certain that all entropy is factually correct , comprehensive , and up to escort . However , this article should not be used as a replacement for the knowledge and expertise of a licensed health care professional . You should always confabulate your doctor or another healthcare professional before taking any medication . The drug information incorporate herein is subject to change and is not think to cover up all possible uses , directions , precautions , warnings , drug interactions , sensitized reactions , or adverse personal effects . The absence of warning or other entropy for a given drug does not indicate that the drug or drug combining is safe , effectual , or appropriate for all patient role or all specific U.S. .
