Kyprolis ( carfilzomib ) is a brand - name injection that ’s order for multiple myeloma in certain situations . Kyprolis has interaction with some other drug . Examples admit combined hormonal birth mastery and clozapine .

Kyprolis is dictate for relapsed or refractorymultiple myelomain adult who have received prior treatment for the precondition . count on how your multiple myeloma was cover in the past tense , Kyprolis may be used alone or in combination with other medications .

Aninteractionoccurs when one substance make another subject matter to have a different effect than expected .

By learning about possible Kyprolis interactions , you may shape with your doctor to insure that Kyprolis will be safe and effective for you to receive . For additional info about Kyprolis , let in details about its usance , see thisKyprolisoverview article .

Kyprolis interactions with other medications

Before you start treatment with Kyprolis , secern your MD and pharmacist which prescription , over - the - counter , and other medications you take . By sharing this info with them , you may help prevent possible interaction . ( To hear whether Kyprolis interact with supplements , herbs , or vitamin , see the “ Kyprolis and other interactions ” department . )

If you have question about drug interaction that may affect you , ask your doctor or druggist .

Here ’s a table of drug that can interact with Kyprolis . Keep in mind that this table does n’t let in all drug that may interact with Kyprolis . Some of these interaction are described in detail in “ Drug interactions in deepness . ”

Kyprolis interaction with alcohol

There are n’t any known interactions between Kyprolis andalcohol . However , your physician may advise you to avoid or limit alcohol consumption during Kyprolis treatment .

This is because drink inebriant while using the drug may worsen some of Kyprolis side effect . For model , you may experience :

In plus , eat up large quantity of alcohol can stimulate liver price . Kyprolis may also cause liver damage as a side effect . This think of that drinking alcohol during Kyprolis handling may increase the hazard of liver problem .

If you consume alcohol during Kyprolis treatment , these side effects may be more potential to occur . If you have questions about drinking alcohol during Kyprolis intervention , talk with your medico .

Drug interactions in depth

Here ’s a closer facial expression at sure drug interactions of Kyprolis .

Combined hormonal birth control

Kyprolis can interact with combined hormonalbirth control . This refers to giving birth control medications that comprise bothestrogenand progestin . In addition to preclude pregnancy , these medication may be order for other uses , such asacne .

fundamental interaction upshot : Using Kyprolis and combined hormonal birth control can kick upstairs the risk of line clots as aside outcome of Kyprolisand birth control pills .

Interaction explained : Both Kyprolis and combine hormonal birth ascendance can rarely cause line of descent clots when used on their own . Taking them together may increase your hazard of this side effect .

example of combined hormonal birth controlmedications : Here are some merge hormonal birth control medication that may interact with Kyprolis :

Steps you or your medico may take : If you ’re prescribed Kyprolis and can become pregnant , your doctor may suggest using a progestogen - only giving birth control pill , such as drospirenone or norethindrone . Progestin - only pills do not carry the same risk of blood line coagulum as immix hormonal birth control pills . Your doctor may also advise other form of birthing control , such ascondoms . mouth with your doctor to take more about your options for birth control if you ’re prescribed Kyprolis .

Clozapine

Kyprolis can interact with clozapine , which is prescribed to treattreatment - immune schizophrenia . It ’s also used to treatsuicidal behavior and ideationsin hoi polloi with schizophrenia .

fundamental interaction result : Using Kyprolis and clozapine can increase the risk of low neutrophile reckoning ( neutropenia ) as a side effect of Kyprolis and clozapine

Interaction explained : Both Kyprolis and clozapine can make neutropenia as a side force when used on their own . Using them together can parent your risk of this side impression .

Steps you or your doctor may take : If you ask to use Kyprolis and clozapine together , your MD may regularize frequent stemma tests to check your neutrophile enumerate throughout treatment .

Kyprolis and other interactions

Kyprolis may have other interactions , such as with supplements , foods , vaccinum , or even lab tests . You ’ll find details below . Keep in thinker that the following information does not let in all other potential interaction with Kyprolis .

Kyprolis interactions with supplements

It ’s potential for drug to interact with supplements such as vitamins andherbs .

There are no specificreportsof herb interacting with Kyprolis . However , that does n’t mean herbal interactions wo n’t occur or be recognize in the future . Because of this , it ’s significant to check with your doctor or apothecary before take any of these production during Kyprolis treatment .

There are no specificreportsof vitamins interacting with Kyprolis . However , that does n’t mean vitamin interaction wo n’t occur or be recognized in the future . Because of this , you should babble out with your doctor or pharmacist before take any vitamin merchandise with Kyprolis .

Kyprolis interactions with food

There were noreportsof food for thought interactions with Kyprolis . If you ’d wish to study more about eating sure foods during treatment with Kyprolis , talk with your doctor .

Kyprolis interactions with vaccines

Kyprolis may interact with livevaccines . A alive vaccine contains live but weakened pieces of the virus or bacterium it ’s mean to support against . When your resistant system is sizable , live vaccines usually wo n’t get infection .

But Kyprolis work by countermine your resistant system . And , it ’s sometimes prescribed with other medications that treat multiple myeloma but can also counteract your resistant system . So if you get a live vaccinum , your resistant system may not be able to campaign the virus or bacterium . This may stimulate you to become sick or develop symptoms of the illness the vaccinum is mean to prevent .

Examples of live vaccines to forfend during Kyprolis treatment let in :

Kyprolis could also move how wellCOVID-19 vaccinationswork , even though these are not live vaccinum . But the voltage for Kyprolis to make COVID-19 vaccinations less effective has beenreported . As a resolution , your doctor may advocate receiving extra Zen of COVID-19 vaccines , found onrecommendationsfrom the Centers for Disease Control and Prevention ( CDC ) .

Before starting Kyprolis , talk with your doctor or chemist about any vaccines you may demand .

Kyprolis interactions with lab tests

Kyprolis is n’t know to interact with any lab test . If you have concerns about this medicine interact with research lab tryout , let the cat out of the bag to your doctor .

Cannabis(often squall marijuana ) and ganja production , such as cannabidiol ( CBD ) , have not been specificallyreportedto interact with Kyprolis . However , as with any drug or supplement , talk with your doctor before using cannabis in combination with Kyprolis . The impact of cannabis may regard how well you bind to your Kyprolis treatment program .

take note : Cannabis is illegal at a federal level but is legal in many states to varying degrees .

Certain medical condition and other factor may increase the risk of interaction with Kyprolis . Before you take in this drug , be certain to speak with your doctor about your wellness history . Kyprolis may not be the right intervention option if you have certain aesculapian precondition or other factors affecting your health .

Health conditions or gene that might interact with Kyprolis admit :

Preventing interactions

you’re able to take certain steps to help prevent interaction with Kyprolis . Your Doctor of the Church and pharmacist are key resource , so make out to them before starting discourse . For example , you should plan to do the following :

It ’s also important to study the Kyprolis recording label and otherpaperworkthat may number with the drug . The label may have colored stickers that mention an interaction . And the paperwork , sometimes bid the medicinal drug guide or patient package cut-in , may contain detail about interaction .

If Kyprolis does n’t come with paperwork , you’re able to ask your pharmacist to print a copy . If you need help reading or sympathise this information , ask your medico or pharmacist .

you’re able to also help prevent fundamental interaction with Kyprolis by using it precisely as your Doctor of the Church prescribes .

Disclaimer : Medical News Today has made every effort to check that that all information is factually correct , comprehensive , and up to date . However , this article should not be used as a substitute for the knowledge and expertise of a licenced healthcare professional . You should always confer your doctor or another healthcare professional before withdraw any medicinal drug . The drug information stop herein is subject to change and is not intended to hide all potential role , direction , precautions , warnings , drug interactions , allergic reactions , or untoward effects . The absence seizure of warnings or other selective information for a devote drug does not indicate that the drug or drug combination is dependable , effective , or appropriate for all patients or all specific uses .