Lutathera is a marque - name solution for IV infusion . It ’s prescribed for sure uncommon cancers that affect the pancreas , tum , intestine , and gut . Lutathera contains the combat-ready ingredient lutetium-177 dotatate .
Drug details
You ’ll find key information about Lutathera below .
Lutathera generic
Lutathera is uncommitted only as a brand name - name medication . It ’s not currently available ingeneric form .
A generic drug is an exact transcript of the alive element in a brand - name medication . Generics unremarkably be less than brand - name drugs .
Lutathera dosage
The following information describes dosage that are usually used or urge . However , your doctor will determine the best dosage to equip your indigence .
Drug form and strength
Lutathera is a character of radiopharmaceutical , meaning it contains an combat-ready drug that releases diminished amounts of actinotherapy . It comes as a liquid solvent in single - use of goods and services vials .
When fix , each phial of Lutathera contains 370 megabecquerels of radioactivity per milliliter ( MBq / mL ) of result . MBq is a unit that measures the amount of radiation in Lutathera .
The radiation of Lutathera decrease over time . To ensure that you receive the right dosage , a trained healthcare professional will measure the radiotherapy of Lutathera in good order before giving the drug .
Each battery-acid of Lutathera is measured in gigabecquerels ( GBq ) . For reference work , 1 GBq is equal to 1,000 MBq .
Dosage for certain neuroendocrine tumors
Lutathera is prescribe to process gastroenteropancreaticneuroendocrine tumors(GEP - NETs ) in certain office . These are rare tumor that move the pancreas , stomach , intestines , and bowel . To learn more , see the “ Lutathera apply ” section .
The common dose of Lutathera for GEP - NETs is 7.4 GBq . You ’ll experience one venereal disease every 8 hebdomad for a amount of four doses .
Your Dr. may give you a different dose depending on the side force you have during discourse . If you have questions about the Lutathera dose that ’s correct for you , talk with your doc .
Children’s dosage
Lutathera is prescribed to treat GEP - NETs in certain fry ages 12 years and older .
The dose of Lutathera for fry is the same as for grownup . For details , see “ dose for sure neuroendocrine tumor . ”
How Lutathera is given
You ’ll pick up Lutathera in a discourse facility that has been train to handle radiopharmaceutical . A healthcare professional will give Lutathera as an intravenous ( IV ) infusion over 30 to 40 transactions .
Your Dr. will cater specific details about your Lutathera treatment protocol . This may let in starting or stopping other medications before , during , and after your extract .
You may also postulate to stay in the adeptness where you received the drug for several hr . This allows your doctor to watch intimately for serious side effect . They ’ll urge how long you should stay in the quickness .
If you have other questions about receive Lutathera , talk with your doctor . you could also confab the drugmanufacturer ’s website .
About receiving Lutathera
Below you ’ll find info about key dosage issues .
Lutathera side effects
Lutathera can cause mild or serious side effects . The following lists check some of the cardinal side effects that may go on during Lutathera discussion . These list do not include all potential side personal effects .
For more information about the potential side effects of Lutathera , utter with your doctor or pharmacist . They can give you crown on how to wield any side effects that may be concerning or annoying .
Note : After the Food and Drug Administration ( FDA ) approves a drug , it tracks and critique side effects of the medication . share your experience avail make medications dependable for everyone by give doctors and investigator more information about how the drug work in real sprightliness . If you educate a side effect during Lutathera treatment and want to tell the FDA about it , visitMedWatchor call 800 - FDA-1088 .
Mild side effects
Below is a partial tilt of mild side effects of Lutathera . To get a line about other mild side personal effects , blab out with your medico or pharmacist or look at Lutathera’sprescribing information .
balmy side effects of Lutathera can include :
Most of these side effect may go away within a few days to a couple of weeks . However , if they become more grave or do n’t go away , talk with your Dr. or pharmacist .
Serious side effects
Serious side essence from Lutathera are n’t vulgar , but they can happen . Call your doctor aright by if you have serious side effects . Call 911 or your local emergency number if your symptoms feel spirit endanger or you think you ’re give birth a medical emergency .
Serious side effects and their symptom can include :
For some masses , Lutathera can cause anallergic reaction . But this side burden was n’t reported in the drug’sclinical test .
In general , symptom of hypersensitised reaction can be mild or serious .
Ways to manage
For mild allergic reaction symptoms , such as a mild rash , call your medico right out . They may advocate treatments to help oneself oversee your symptoms . They ’ll also lease you know whether you should continue receiving the medicine .
For stark allergic chemical reaction symptom , such as swelling or trouble breathing , call 911 or your local emergency number right away . These symptom require immediate medical forethought because they can become life threatening . If you ’ve had a serious allergic response to Lutathera , your doctor may recommend a different medication instead .
Lutathera uses
The Food and Drug Administration ( FDA ) O.K. prescription drugs such as Lutathera to treat sure shape .
Lutathera for certain neuroendocrine tumors
Lutathera is approved to treat gastroenteropancreatic neuroendocrine tumors ( GEP - NETs ) in adults . For this use , the Crab must be somatostatin sensory receptor - positive . This mean the tumour has receptors ( attachment sites ) for a hormone call somatostatin .
GEP - NETs are rare tumors that affect the pancreas , stomach , bowel , and bowel . symptom may include diarrhea , abdominal pain , and unintended weight deprivation .
To ascertain more about Lutathera for GEP - NETs , lecture with your Dr. .
Lutathera and children
Lutathera is approved to treat GEP - NETs in children age 12 years and elder . For this use , the cancer must be somatostatin receptor - positivist .
To learn more about this purpose , see “ Lutathera for sure neuroendocrine tumors ” above . you could also talk with your child ’s doctor .
Lutathera interactions
Lutathera caninteractwith several other medications . It ’s not known to interact withsupplementsor foods .
Before receive Lutathera , talk with your MD and chemist . Tell them about all prescription , over - the - counter , and other drugs you take . Also tell them about anyvitamins , herbs , andsupplementsyou take . Sharing this information can help you invalidate likely interactions .
Interactions with medications
Below is a inclination of medication that can interact with Lutathera . This list does not contain all drug that may interact with Lutathera . If you have motion about drug interaction that may affect you , ask your doctor or pharmacist .
Alcohol interaction
Alcohol is not have it off to interact with Lutathera . However , drinking alcoholic beverage may exasperate certain side effect of the drug , including lightheadedness , headache , and diarrhea .
If you booze alcohol , speak with your doctor about how much is safe for you to drink during Lutathera discussion .
Lutathera cost and coupons
As with all medicine , the cost of Lutathera can vary . The actual price you ’ll yield depends on yourinsuranceplan and your location .
Financial and indemnity assistance : If you ask fiscal support to pay for Lutathera or need help understanding your insurance reporting , help is usable .
A program called Novartis Patient Support is available for Lutathera . For more data and to witness out if you ’re eligible for backing , call 844 - 638 - 7222 or visit theprogram website .
Generic variant : Lutathera is not available in agenericform . A generic drug is an precise transcript of the active element in a brand - name medication . Generics tend to be less than brand - name drugs .
memorise money on prescription drug .
Lutathera alternatives
Other drugs are available that can treat gastroenteropancreatic neuroendocrine tumors ( GEP - NETs ) . Some may be a better set for you than others . If you ’re concerned in find an alternative to Lutathera , spill the beans with your Dr. . They can tell you about other medications that may cultivate well for you .
illustration of drugs that are alternative to Lutathera include :
Things to consider when receiving Lutathera
If you’re able to become meaning , consider the follow information about pregnancy , fertility , nativity ascendancy , and wet-nurse .
Note : Sex and genderexist on spectrums . Use of the full term “ female ” and “ male person ” in this clause refers to sexual practice ascribe at parentage .
Lutathera and pregnancy
It ’s not known whether Lutathera is secure to get during pregnancy . Because of the manner the drug works , Lutathera may cause harm to a fetus . To be secure , your doctor may give notice you not to get the drug while pregnant .
If you ’re be after a gestation or can become pregnant , mouth with your doctor before pick up Lutathera . Your MD may have you take a gestation test before starting treatment .
Lutathera and fertility
Lutathera may causeinfertility(an inability to conceive ) in male and females . This outcome may be irregular or permanent .
If you have questions about Lutathera and fertility , talk with your doctor .
Lutathera and birth control
It ’s not known whether Lutathera is good to receive during pregnancy . If you ’re sexually active and you or your spouse can become significant , talk with your MD about yourbirth controlneeds during Lutathera discussion .
If you ’re a female who can become pregnant and you occupy in sexual activity that could lead to pregnancy , you should use effective birth mastery during Lutathera treatment . You should continue using birth ascendancy for at least 7 months after your final venereal disease of the drug .
If you ’re a male person with a sexual partner who can become pregnant , you should apply in effect birth control ( such as condoms ) during Lutathera treatment . You should continue to utilise birth control condition for at least 4 calendar month after your concluding dose of the drug .
Lutathera and breastfeeding
It ’s not known whether Lutathera should be used while breastfeeding . To be good , your doctor may advise you to avoid suck during treatment and for at least 2.5 calendar month after your net sexually transmitted disease .
If you ’re currently suckle or planning to do so , sing with your doctor before receiving this medication . They may recommend other way to eat a shaver who is breastfed .
How Lutathera works
Lutathera is used to treat gastroenteropancreatic neuroendocrine tumors ( GEP - NETs ) in grownup . These are rare tumor that strike the pancreas , stomach , intestines , and bowel .
For this use , the Cancer the Crab must be somatostatin receptor - positive . This means the tumour has sense organ ( bond internet site ) for a hormone called somatostatin .
Lutathera is a type of radiopharmaceutical , meaning it curb an active drug that releases small measure of radiation sickness . Its mechanism of action ( how it works ) is to bind to somatostatin sense organ on genus Cancer cell . Lutathera then enters the malignant neoplastic disease cells and releases radiotherapy to shoot down them .
If you have other questions about how Lutathera works , utter with your doctor . you could also inflict the drugmanufacturer ’s web site .
Common questions about Lutathera
Here are reply to some frequently call for question about Lutathera .
How does Lutathera compare with Pluvicto?
Both Lutathera andPluvictoare radiopharmaceuticals . Each contains a soma of lutetium-177 as the alive drug .
However , Lutathera and Pluvicto have unlike use . Lutathera is used to process certain gastroenteropancreatic neuroendocrine neoplasm . Pluvicto is used to treatmetastatic prostate cancerin certain situations .
To learn more about how Lutathera and Pluvicto compare , verbalize with your Dr. .
Is Lutathera a type of chemotherapy or another cancer treatment?
No , Lutathera is not a character ofchemotherapy . Instead , it ’s a radiopharmaceutical that delivers targetedradiation therapyto Cancer the Crab cadre .
Chemotherapy knead by attacking rapidly dividing cell , including genus Cancer cells and some healthy cells . Lutathera works differently . It attach to Crab cell and relinquish radiation to shoot down them .
If you have questions about Lutathera and chemotherapy , talk with your doc .
Should I follow any guidance on radiation safety with Lutathera?
Yes , you should play along radiation base hit recitation after Lutathera intervention . This is because small sum of radiation sickness leave your trunk through urine , sweat , and other fluids for a short time . While the risk of infection to others is down , taking precaution help reduce photo to those around you .
Below are the forethought you might come after with Lutathera :
The treatment adeptness where you ’ll receive Lutathera may have other safety instructions . If you have question , verbalise with your MD .
Lutathera precautions
Before receive Lutathera , discuss your wellness story with your physician . Lutathera may not be proper for you if you have certain medical term or other factors impress your wellness . Be sure to talk with your doctor if any of the following apply to you :
Note : For more information about the possible negatively charged effects of Lutathera , see the “ Lutathera side effects ” section .
Disclaimer : Medical News Today has made every effort to verify that all information is factually correct , comprehensive , and up to particular date . However , this article should not be used as a substitute for the knowledge and expertise of a licenced healthcare professional . You should always look up your medico or another healthcare professional before taking any medication . The drug information contained herein is subject to modification and is not stand for to cover all possible uses , directions , caution , warnings , drug interactions , supersensitized response , or adverse effects . The absence of warnings or other information for a given drug does not indicate that the drug or drug combining is secure , in effect , or appropriate for all patients or all specific uses .
