Pemazyre has possible interactions with some other drugs and certain appurtenance . representative include phenytoin , diltiazem , and St. John ’s wort . Talk with your doctor to avoid potentially harmful effects from Pemazyre interaction .

Pemazyre is prescribed to address sure types of cancer in adults , including :

Aninteractionoccurs when one substance causes another substance to have a unlike consequence than expected .

By pick up about possible Pemazyre fundamental interaction , you’re able to work out with your doctor to ensure Pemazyre will be safe and effective for you to take .

  • For this use , Pemazyre has receivedaccelerated approvalfrom the Food and Drug Administration ( FDA ) . This means the drug has been approve for this purpose based on limited data from early clinical trials . A decision regarding full commendation will be made once extra clinical tryout have been completed .

Pemazyre interactions with other drugs

Before you start discussion with Pemazyre , tell your doctor and druggist about any prescription drug , over - the - counter , and other medications you take . By sharing this information with them , you may help oneself prevent potential interactions .

To teach whether Pemazyre interacts with supplements , herbs , or vitamin , see the “ Pemazyre and other fundamental interaction ” section .

If you have questions about drug interactions that may affect you , ask your doctor or pharmacist .

Here ’s a table of drug that can interact with Pemazyre . Keep in mind this table does n’t include all drug that may interact with Pemazyre . Some of these interactions are described in item in “ Drug interactions in depth . ”

Pemazyre and alcohol

There are no known interactions between Pemazyre andalcohol . However , if you drink intoxicant , your Dr. may advise you to void or restrict it during Pemazyre treatment .

This is because drink inebriant while taking the drug may exacerbate some of Pemazyre ’s side effect . For illustration , you may be more likely to live :

If you have questions about drinking alcohol while take Pemazyre , mouth with your Doctor of the Church .

Drug interactions in depth

Here ’s a closemouthed look at sure drug interactions of Pemazyre .

Certain calcium channel blockers

Taking Pemazyre with sure calcium groove blocker can increase the risk of side force of Pemazyre . This is because some calcium line blockers can cause your body to break out down Pemazyre more slow . When this materialize , more of the drug stays in your system . This can contribute to a high risk of side effect from Pemazyre , such asfatigue , hair loss , and sass sore .

Here are some atomic number 20 duct blockers that may interact with Pemazyre :

Your physician will likely avoid prescribing Pemazyre with certain calcium channel blockers . If you are taking a calcium TV channel blocker that interacts with Pemazyre , they may have you trade to a different medication before order Pemazyre for you . However , if they settle you must take a Ca television channel blocking agent that interacts with Pemazyre , your doc will likely prescribe a lower dose of Pemazyre to repress the jeopardy of side effects .

Talk with your MD or pharmacist if you have questions or concerns about taking Pemazyre with a calcium duct blocker .

Certain seizure medications

Taking Pemazyre with sure seizure medications can make Pemazyre less effective . This is because some ictus medication can induce your consistence to smash down Pemazyre quicker than usual , reducing the amount of drug in your system . As a issue , Pemazyre may be less in effect in treating your cancer .

Here are some seizure medications that may interact with Pemazyre :

Your doctor will likely avoid prescribing Pemazyre with sealed seizure medications . If you are consider a seizure medicament that interact with Pemazyre , they may have you switch to a different medication to handle your seizures before prescribing Pemazyre for you .

lecture with your doctor or pharmacist . If you have questions or vexation about taking Pemazyre with a seizure medicinal drug .

Certain antifungal medications

take Pemazyre with certain fungicidal medications can increase the risk of side effects of Pemazyre . This is because some antifungals can cause your eubstance to break down Pemazyre more slowly . When this happens , more of the drug stays in your system . This can extend to a high risk of side effects from Pemazyre , such as fatigue , whisker loss , and mouth sores .

Here are some antifungals that may interact with Pemazyre :

If you have a fungous infection , your doctor will in all likelihood attempt to void prescribing an fungicidal medication that interacts with Pemazyre . But if they decide it ’s necessary to use one of these antifungals , your doc may lower your superman of Pemazyre while you ’re taking the fungicidal . After your infection has cleared and you stop taking the antifungal , your doctor will likely increase Pemazyre back to your original dosage .

Talk with your MD or pharmacist if you have questions about occupy Pemazyre with an antifungal drug .

Pemazyre and other interactions

Pemazyre may have other interaction , such as with supplements , food , vaccines , or research lab tests .

Here are some potential interactions with Pemazyre . Keep in mind that the watch over selective information does not let in all possible Pemazyre interactions .

Pemazyre interactions with supplements

Before you start treatment with Pemazyre , tell your doctor and pharmacist about anysupplements , herbs , and vitaminsyou take . By share this data with them , you may avail preclude potential interactions .

doctor will typically recommend that you avoid takingSt . John ’s wortwith Pemazyre . St. John ’s wort is an herbal add-on that some people use to treatdepressionand other conditions .

St. John ’s wort may speed up up the natural action of anenzymein your body called cytochrome P450 3A4 ( CYP3A4 ) . This enzyme helps give away down Pemazyre .

By speeding up this enzyme , St. John ’s wort can stimulate Pemazyre to break down more apace . And this may go to a low grade of Pemazyre in your organization . If the floor of Pemazyre in your system is too down in the mouth , the drug may not work to treat your cancer .

Your medico may be able to suggest a treatment alternative other than St. John ’s wort .

There are no specificreportsof vitamins interact with Pemazyre . However , that does n’t mean vitamin interactions wo n’t occur or be recognized in the time to come . Because of this , you should talk with your physician or pharmacist before taking any vitamin product with Pemazyre .

Pemazyre interactions with food

Grapefruitand grapefruit juice can interact with Pemazyre . Specifically , grapefruit products can block the CYP3A4 enzyme , which facilitate to break down Pemazrye . This can raise the level of Pemazyre in your body , which increases your risk of side effects from Pemazyre . Due to this danger , your doc may recommend not have Citrus paradisi and Citrus paradisi juice while taking the drug .

Pemazyre interactions with vaccines

There are no known interaction between Pemazyre andvaccines . Talk with your doctor or pill roller to check whether you ’re due for any vaccinum .

Pemazyre interactions with lab tests

Pemazyre is not known to interact with research lab examination . If you have concerns about this medication interacting with research laboratory tests , talk with your doctor .

Cannabis(often call marijuana ) and cannabis product , such as cannabidiol ( CBD ) , have not been specificallyreportedto interact with Pemazyre . However , as with any drug or supplement , verbalize with your physician before using cannabis in combination with Pemazyre . The impact of cannabis may affect how well you amaze to your Pemazyre discussion plan .

Note : Cannabis is illegal at a Union level but is legal in many states to vary degrees .

Certain aesculapian conditions and other factors may increase the risk of interactions with Pemazyre . Before you take this drug , be sure to talk with your doctor about your wellness history . Pemazyre may not be the right treatment choice if you have sealed aesculapian conditions or other factors affecting your health .

wellness conditions or factors that might interact with Pemazyre include :

FAQs about Pemazyre and interactions

Here are some frequently require doubt about Pemazyre and possible interaction .

Does Pemazyre interact with diabetes medications?

No , Pemazyre has not beenreportedto interact with diabetes medications . But it can cause side event like loss of appetite or free weight going , which may affect blood sugar regulation . Pemazyre can also increase roue sugar in some masses . If you have diabetes , your doctor may recommend monitor your ancestry sugar storey more frequently while taking Pemazyre .

Talk with your doctor or pharmacist if you have questions about taking diabetes medicinal drug or monitor your rakehell sugar during treatment with Pemazyre .

Do pain relievers like ibuprofen or acetaminophen interact with Pemazyre?

No , there were n’t any drug interactionsreportedwith over - the - buffet pain relievers like ibuprofen or acetaminophen . However , since Pemazyre can affect the liver , taking too much acetaminophen may increase the risk of liver damage . If you need to take acetaminophen , it ’s best to employ it in moderation and follow the urge dosage .

If you have any motion about taking an over - the - counter pain medicine , talk with your doctor or pharmacist .

Preventing interactions

you may take certain steps to aid prevent interaction with Pemazyre . Your doctor and pharmacist are cardinal resource , so attain out to them before starting treatment is a helpful first step . For example , it ’s significant that you plan to do the following :

It ’s also important to read the Pemazyre recording label and otherpaperworkthat may amount with the drug . The recording label may have colored sticker that advert an fundamental interaction . The paperwork , sometimes call the medicinal drug guide or patient software package insert , may carry inside information about interaction .

If Pemazyre does n’t amount with paperwork , you may expect your druggist to impress a copy . If you need help reading or understand this information , ask your medico or chemist .

you could also help foreclose interactions with Pemazyre by taking it exactly as your doctor prescribes .

Disclaimer : Medical News Today has made every endeavor to make certain that all information is factually correct , comprehensive , and up to date . However , this clause should not be used as a relief for the cognition and expertise of a licensed healthcare professional . You should always consult your Doctor of the Church or another healthcare professional before take any medication . The drug information contained herein is subject to modification and is not intend to cover all potential uses , directions , precautions , warning , drug interactions , allergic reactions , or adverse personal effects . The absence of warnings or other information for a sacrifice drug does not indicate that the drug or drug combination is safe , effective , or appropriate for all patient or all specific uses .