Tysabri ( natalizumab ) is a brand - name endovenous ( IV ) infusion . It ’s prescribed for adults with Crohn ’s disease or certain forms of multiple sclerosis . Tysabri has interaction with some other drugs . Examples include prednisone ( Rayos ) and adalimumab ( Humira ) .

Aninteractionoccurs when one core do another means to have a different effect than expect .

By learning about possible Tysabri interaction , you’re able to work with your doctor to ensure Tysabri will be safe and effective for you to incur . For additional information about Tysabri , including details about its usance , see thisTysabrioverview clause .

Tysabri interactions with other medications

Before you start handling with Tysabri , say your physician and pharmacist which prescription , over - the - buffet , and other medicament you take . By share this data with them , you may help prevent possible interactions . ( To get word whether Tysabri interact with supplementation , herbs , or vitamins , see the “ Tysabri and other fundamental interaction ” part . )

If you have interrogative sentence about drug interactions that may affect you , ask your doctor or pharmacist .

Here ’s a table of drug that can interact with Tysabri . Keep in brain that this table does n’t include all drugs that may interact with Tysabri . Some of these interaction are described in point in “ Drug fundamental interaction in depth . ”

remark : Tysabri has aboxed warningabout the risk of a rarefied but serious mastermind contagion calledprogressive multifocal leukoencephalopathy ( PML ) . For contingent , see the boxed in monition at the top of this clause .

When to avoid Tysabri

In some cases , factors or condition could foreclose your doctor from prescribing Tysabri due to the risk of harm . These are know as contraindications . The contraindications of Tysabri include :

Having current or pastprogressive multifocal leukoencephalopathy(PML)

Doctors typically wo n’t dictate Tysabri for citizenry who ’ve ever had a rarified but serious brain transmission calledPML . This is because Tysabri has aboxed warningabout the endangerment of PML . A boxed warning is the most serious warning from the Food and Drug Administration ( FDA ) . For details , see “ boxed-in word of advice ” at the get-go of this clause .

Having had an allergic reaction to Tysabri or any of its ingredients

If you have had anallergic reactionto Tysabri or any of its ingredient , your doctor will in all probability not prescribe Tysabri . encounter the drug could cause another allergic response . you’re able to ask them about other treatments that may be good choice for you .

observe : Before you set forth treatment with Tysabri , it ’s important to recite your doctor if these contraindications apply to you . They can check whether to prescribe Tysabri .

Tysabri and alcohol

There are n’t any live interaction between Tysabri andalcohol . However , there may be somerisksto combining Tysabri and alcohol . For this reason , your MD may apprise you to avoid or limit alcohol consumption during Tysabri treatment .

Specifically , alcohol may worsen symptoms of the condition you ’re receiving Tysabri to treat . To learn more , you’re able to view these article aboutalcohol and Crohn ’s diseaseoralcohol and multiple sclerosis .

Drinking alcohol during handling with the drug may also aggravate some ofTysabri ’s side effects . For example , you may have decline headache orfatigue .

In addition , consuming large amounts of alcohol can cause liver price . Tysabri may also cause liver damage as a side burden . This means that drinking alcohol during Tysabri treatment may increase the risk of liver problems .

If you have doubtfulness about restrain alcoholic drink during Tysabri discussion , talk with your doctor .

Drug interactions in depth

Here ’s a closemouthed look at certain drug interactions of Tysabri .

Corticosteroids

Corticosteroidsare prescribed for conditions involving fervor . This includes the same conditions Tysabri is order to treat .

fundamental interaction result : Taking a corticosteroid with Tysabri may increase the danger of infection as a side effect of either drug .

Interaction explained : Both Tysabri and corticosteroids can lower the resistant system ’s power to fight back contagion . intervention with either drug alone may increase your peril of infection . However , this peril is even greater when these drugs are taken together .

In fact , Tysabri has aboxed warningabout the endangerment of a serious mental capacity transmission calledprogressive multifocal leukoencephalopathy ( PML ) . A boxed monition is the most serious monition from the FDA . For inside information , see “ Boxed word of advice ” at the beginning of this article .

deterrent example of corticosteroid drugs : Here are some corticosteroids that may interact with Tysabri :

Steps you or your Doctor of the Church may take : Before starting Tysabri treatment , evidence your Dr. if you ’re taking a corticosteroid . They can urge whether it ’s dependable to take it with Tysabri .

If your Dr. prescribe Tysabri with a corticosteroid , they ’ll discuss your hazard of contagion . They may slowly bring down your corticosteroid dose over metre until the drug is stopped .

If you have symptoms of an transmission while taking these drug together , lecture with your doctor . They can give you trial run to check for an infection and advocate what to do if you have one .

To instruct more about Tysabri and corticoid , talk with your doctor or apothecary .

Tumor necrosis factor (TNF) blockers

TNFblockers are prescribed for many autoimmune conditions . This includesCrohn ’s disease , which Tysabri is also dictate to treat .

Interaction result : Treatment with Tysabri and TNF blocker can increase the risk of infection as a side gist of either medication .

Interaction explained : Tysabri and TNF blocking agent can lower the ability of your immune system to fight against infection . As a solvent , either drug can increase your peril of infection when used alone . Using these drug together further increase this jeopardy .

Keep in mind that Tysabri has aboxed warningabout the risk of a serious nous infectionPML . For details , see “ Boxed warning ” at the get-go of this clause .

Examples of TNF blocker drugs : Here are some TNF blocker that may interact with Tysabri :

dance step you or your doctor may take : Before get going Tysabri discourse , distinguish your doctor about other medications you take . They can help you ascertain if you ’re prescribed a TNF blocking agent .

Your doctor is improbable to order Tysabri with a TNF blocking agent . Your doctor can recommend which drug is right for your condition .

To get word more about Tysabri and TNF blockers , talk with your doctor or druggist .

Ozanimod

Like Tysabri , ozanimod ( Zeposia ) is dictate for certain types ofmultiple sclerosis .

Interaction result : Treatment with Tysabri and ozanimod may increase the risk of infection .

Interaction explain : Both Tysabri and ozanimod may increase your risk of infection when used individually . This endangerment is even smashing when these drugs are taken together .

It ’s crucial to note that Tysabri has aboxed warningabout the jeopardy of a serious brain infection calledPML . For details , see “ Boxed warning ” at the beginning of this article .

Steps you or your physician may take : Before set about Tysabri discussion , recount your MD if you take ozanimod . They ’re improbable to prescribe these drugs together . Your doctor can determine whether Tysabri or ozanimod is the good treatment option .

To learn more about Tysabri and ozanimod , talk with your doctor or pharmacist .

Tysabri and other interactions

Tysabri may have other interactions , such as with supplements , foods , vaccine , or even lab tests . You ’ll find details below . Keep in intellect that the following entropy does not include all other possible interactions with Tysabri .

Tysabri and supplements

It ’s possible for drug to interact with supplements such as vitamins andherbs .

There are no specificreportsof herbs interacting with Tysabri . However , that does n’t stand for herbal interactions wo n’t come or be recognized in the hereafter . Because of this , it ’s authoritative to check with your doctor or pharmacist before make any of these merchandise during Tysabri handling .

There are no specificreportsof vitamins interact with Tysabri . However , that does n’t mean vitamin interaction wo n’t occur or be recognized in the future . Because of this , you should talk with your doctor or pharmacist before taking any vitamin product with Tysabri .

Tysabri and food

There were noreportsof solid food interactions with Tysabri . If you ’d like to see more about eating certain foods during treatment with Tysabri , blab out with your doctor .

Tysabri interactions with vaccines

Tysabri may interact with live vaccines . A live vaccinum contains a break form of the computer virus or bacteria it ’s imply to maintain against . When your resistant system is hefty , hot vaccines usually wo n’t cause infection .

But Tysabri may lower the power of your resistant system to fight contagion . So if you get a live vaccine during Tysabri treatment , your resistant system may not be capable to fight back the virus or bacteria . This may make you to arise symptom of the illness the vaccine is mean to hold against .

illustration of resilient vaccinum to avoid during Tysabri discussion admit :

Before begin Tysabri , mouth with your doctor or chemist about any vaccine you may ask .

Tysabri and lab tests

Tysabri is n’t known to interact with any lab tests . If you have concerns about this medication interacting with lab tests , talk with your doctor .

Cannabis(often name marijuana ) and marihuana mathematical product , such as cannabidiol ( CBD ) , have not been specificallyreportedto interact with Tysabri . However , as with any drug or supplement , babble out with your doctor before using hemp in compounding with Tysabri . The impingement of cannabis may touch how well you stick to your Tysabri handling programme .

mark : Cannabis is illegal at a federal spirit level but is sound in many states to variegate degrees .

Certain aesculapian condition and other factors may increase the risk of fundamental interaction with Tysabri . Before you take this drug , be sure to talk with your doctor about your health history . Tysabri may not be the right treatment option if you have certain medical conditions or other factors affecting your health .

Health condition or factors that might interact with Tysabri include :

Preventing interactions

you’re able to take sure whole tone to help prevent interactions with Tysabri . Your physician and pharmacist are key resources , so arrive at out to them before starting discourse . For representative , you should plan to do the following :

It ’s also important to read the Tysabri recording label and otherpaperworkthat may amount with the drug . The label may have colored spine that mention an interaction . And the paperwork , sometimes called the medicament guide or patient package insert , may contain point about interaction .

If Tysabri does n’t come with paperwork , you may ask your pharmacist to impress a written matter . If you need help reading or understanding this information , require your Doctor of the Church or pharmacist .

Disclaimer : Medical News Today has made every effort to ensure that all information is factually correct , comprehensive , and up to day of the month . However , this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional . You should always consult your Dr. or another healthcare professional before taking any medicinal drug . The drug information check herein is subject to modification and is not intended to continue all possible uses , counselling , forethought , warnings , drug interaction , allergic reaction , or adverse personal effects . The absence of warnings or other data for a given drug does not point that the drug or drug combination is safe , effectual , or appropriate for all patients or all specific usage .